Assistant Clinical Professor of Medicine at the University of
California Medical School, Irvine California
ABSTRACT:
Eighteen patients with documented arteriosclerotic heart disease were studied utilizing the isotope technetium 99m to measure left ventricular ejection fraction before and after the administration of EDTA chelation therapy. A statistically significant improvement in left ventricular ejection fraction occurred in this group of patients.
Ejection Fraction Measured by Technetium 99m Before and After Chelation Therapy*
| Patient |
Age |
Sex |
Before |
After |
Change* |
# Treatments |
| 1. RH |
59 |
M |
51% |
62% |
+11% |
20 |
| 2. RS |
65 |
M |
35% |
40% |
+ 5% |
20 |
| 3. ES |
54 |
M |
55% |
71% |
+16% |
20 |
| 4. MW |
72 |
F |
59% |
61% |
+ 2% |
20 |
| 5. GB |
75 |
F |
74% |
77% |
+ 3% |
20 |
| 6. SW |
45 |
M |
53% |
65% |
+ 12% |
20 |
| 7. HH |
72 |
F |
59% |
69% |
+ 10% |
18 |
| 8. MB |
73 |
F |
46% |
61% |
+ 15% |
20 |
| 9. DF |
60 |
F |
61% |
68% |
+ 7% |
4 |
| 10. KS |
57 |
F |
76% |
77% |
+ 1% |
20 |
| 11. MC |
57 |
F |
73% |
79% |
+ 6% |
20 |
| 12. UG |
72 |
F |
63% |
64% |
+ 1% |
16 |
| 13. ND |
67 |
M |
63% |
66% |
+ 3% |
20 |
| 14. CA |
56 |
M |
64% |
65% |
+ 1% |
20 |
| 15. AA |
55 |
F |
65% |
68% |
+ 3% |
20 |
| 16. RP |
48 |
F |
58% |
56% |
- 2% |
20 |
| 17. AC |
52 |
M |
58% |
61% |
+ 3% |
20 |
| 18. JR |
47 |
M |
63% |
70% |
+ 7% |
20 |
Mean Change + 5.77%
Range - 2 to + 16% (P < 0.0005)
*Studies performed at Nuclear Medicine Department Long Beach Community Hospital using 20 millicuries technetium 99m glucoheptonate. Unless otherwise indicated, treat-ment consisted of 20 IV infusions of 3 gm EDTA.
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